Yee-Shin Lin, Ph.D.
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林以行 |
Yee-Shin Lin, Ph.D. |
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Tel (Office) |
886-6-235 3535 ext. 5646 |
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Tel (Lab.) |
886-6-235 3535 ext. 5645、5647 |
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FAX |
(06) 208 2705 |
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yslin1@ mail.ncku.edu.tw |
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現職年月 |
特聘教授(2002/08) |
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EDUCATION
1973-1977 B.S., Department of Biology, National Taiwan Normal University,Taipei, Taiwan, ROC
1979-1982 M.S., Department of Microbiology, California State University Long Beach, CA, USA
1982-1986 Ph.D., Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, USA
PROFESSIONAL EXPERIENCE
2012 Director, Center of Infectious Disease and Signaling Research, National Cheng Kung University Medical College, Tainan, Taiwan
2002-present Distinguished Professor, Department of Microbiology and Immunology, National Cheng Kung University Medical College, Tainan, Taiwan, ROC
1992-present Professor, Department of Microbiology and Immunology, National Cheng Kung University Medical College, Tainan, Taiwan, ROC
1987-1992 Associate Professor, Department of Microbiology and Immunology, National Cheng Kung University Medical College, Tainan, Taiwan, ROC
1986-1987 Lecturer, Department of Microbiology and Immunology, National Cheng Kung University Medical College, Tainan, Taiwan, ROC
1982-1986 Graduate Assistant, Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, USA
1981-1982 Graduate Assistant, Department of Microbiology, California State University Long Beach, CA, USA
1980 Research Assistant, Department of Microbiology, California State University Long Beach, CA, USA
1977-1979 Biology and Chemistry Teacher, Tainan First Senior High School, Tainan, Taiwan, ROC
專長學門
免疫學；感染與免疫
研究興趣
登革病毒致病機制及疫苗研發。
A群鏈球菌感染之致病機轉。
細胞凋亡機制及訊息傳遞。
PUBLICATIONS
1. Lin, Y. S., and T. J. Rogers. 1986. Inhibition of antibody production from the plasmacytoma cell line MOPC-315 by staphylococcal enterotoxin B-induced T-suppressor cells. Cell. Immunol. 102:299-306. (SCI)
2. Lin, Y. S., M. R. Patel, T. J. Linna, and T. J. Rogers. 1986. Suppression of cytotoxic T-cell activity by staphylococcal enterotoxin B-induced suppressor cells: role of interleukin 2. Cell. Immunol. 103:147-159. (SCI)
3. Holly, M., Y. S. Lin, and T. J. Rogers. 1988. Induction of suppressor cells by staphylococcal enterotoxin B: identification of a suppressor cell circuit in the generation of suppressor-effector cells. Immunology 64:643-648. (SCI)
4. Lin, Y. S., M. T. Largen, J. R. Newcomb, and T. J. Rogers. 1988. Production and characterization of monoclonal antibodies specific for staphylococcal enterotoxin B. J. Med. Microbiol. 27:263-270. (SCI)
5. Taub, D. D., Y. S. Lin, S. C. Hu, and T. J. Rogers. 1989. Immunomodulatory activity of staphylococcal enterotoxin-B: the induction of an I-J-restricted suppressor factor. J. Immunol. 143:813-820. (SCI)
6. Taub, D. D., Y. S. Lin, and T. J. Rogers. 1990. Characterization and genetic restriction of suppressor-effector cells induced by staphylococcal enterotoxin B. J. Immunol. 144:456-462. (SCI)
7. Newcomb, J. R., Y. S. Lin, and T. J. Rogers. 1990. Requirement for accessory cells in suppression of MOPC-315 IgA secretion by staphylococcal enterotoxin B-induced T-suppressor cells. Cell. Immunol. 129:528-537. (SCI)
8. Low, T. L. K., T. L. Pan, and Y. S. Lin. 1990. Depression of prothymosin alpha production in murine thymus correlates with staphylococcal enterotoxin B-induced immunosuppression. FEBS Lett. 273:1-5. (SCI)
9. Patel, M., D. D. Taub, Y. S. Lin, and T. J. Rogers. 1990. Immunosuppressive activity of staphylococcal enterotoxin B. I. Characterization of staphylococcal enterotoxin-B-induced suppressor cells. Cell. Immunol. 131:159-169. (SCI)
10. Taub, D. D., Y. S. Lin, and T. J. Rogers. 1990. Immunosuppressive activity of staphylococcal enterotoxin B. II. Activation of suppressor-effector cells by a staphylococcal enterotoxin-B-induced suppressor factor. Cell. Immunol. 131:170-183. (SCI)
11. Lin, Y. S., S. C. Hu, M. S. Jan, and T. J. Rogers. 1991. Inhibition of the delayed-type hypersensitivity response by staphylococcal enterotoxin B-induced suppressor T cells. Cell. Immunol. 132:532-538. (SCI)
12. Lin, Y. S., H. Y. Lei, T. L. K. Low, C. L. Shen, L. J. Chou, and M. S. Jan. 1992. In vivo induction of apoptosis in immature thymocytes by staphylococcal enterotoxin B. J. Immunol. 149:1156-1163. (SCI)
13. Lin, Y. S., H. C. Chiang, W. S. Kan, E. Hones, S. J. Shih, and M. H. Won. 1992. Immunomodulatory activity of various fractions derived from Physalis angulata L extract. Am. J. Chin. Med. 20:233-243. (SCI)
14. Lin, Y. S., M. S. Jan, and H. I. Chen. 1993. The effect of chronic and acute exercise on immunity in rats. Int. J. Sports Med. 14:86-92. (SCI)
15. Wang, S. D., K. J. Huang, Y. S. Lin, and H. Y. Lei. 1994. Sepsis-induced apoptosis of the thymocytes in mice. J. Immunol. 152:5014-5021. (SCI)
16. Kao, S. F., H. L. Kuo, Y. C. Lee, H. C. Chiang, and Y. S. Lin. 1994. Immunostimulation of Alsophila spinulosaextract fraction VII on both humoral and cellular immune responses. Anticancer Res. 14:2439-2444. (SCI)
17. Lin, Y. S., S. F. Kao, M. S. Jan, M. L. Cheng, L. Y. C. Wing, W. C. Chang, H. Y. Lei, and M. T. Lin. 1995. Changes of protein kinase C subspecies in staphylococcal enterotoxin B-induced thymocyte apoptosis. Biochem. Biophys. Res. Commun. 213:1132-1139. (SCI)
18. Lin, Y. S., M. S. Jan, T. J. Tsai, and H. I. Chen. 1995. Immunomodulatory effects of acute exercise bout in sedentary and trained rats. Med. Sci. Sports Exerc. 27:73-78. (SCI)
19. Tsao, C. W., J. T. Cheng, C. L. Shen, and Y. S. Lin. 1996. 6-Hydroxydopamine induces thymocyte apoptosis in mice. J. Neuroimmunol. 65:91-95. (SCI)
20. Hu, H. L., W. D. Cornwell, T. J. Rogers, and Y. S. Lin. 1996. In vivo analysis of a superantigen-induced T cell suppressor factor. Cell. Immunol. 167:285-292. (SCI)
21. Chou, M. C., S. C. Lee, Y. S. Lin, and H. Y. Lei. 1997. Vb8+CD4-CD8- subpopulation induced by staphylococcal enterotoxin B. Immunol. Lett. 55:85-91. (SCI)
22. Liu, M. F., J. S. Li, Y. S. Lin, and H. Y. Lei. 1997. Lack of evidence for the role of staphylococcal enterotoxins in rheumatoid arthritis. Clin. Exp. Rheum. 15:67-70. (SCI)
23. Tsao, C. W. Y. S. Lin, and J. T. Cheng. 1997. Effect of dopamine on immune cell proliferation in mice. Life Sci. 61:PL361-371. (SCI)
24. Hsu, C. C., Y. S. Lin, S. T. Wang, and K. E. Huang. 1997. Immunomodulation in women with endometriosis receiving GnRH agonist. Obstet. Gynecol. 89:993-998. (SCI)
25. Lin, Y. S., K. H. Chen, C. F. Kuo, K. J. Huang, and J. J. Wu. 1998. Induction of thymocyte apoptosis in mice byYersinia enterocolitica products. J. Med. Microbiol. 47:447-454. (SCI)
26. Tsao, C. W., Y. S. Lin, and J. T. Cheng. 1998. Inhibition of immune cell proliferation with haloperidol and relationship of tyrosine hydroxylase expression to immune cell growth. Life Sci. 62:PL335-344. (SCI)
27. Tsai, P. J., C. F. Kuo, K. Y. Lin, Y. S. Lin, H. Y. Lei, F. F. Chen, J. R. Wang, and J. J. Wu. 1998. Effect of group A streptococcal cysteine protease on invasion of epithelial cells. Infect. Immun. 66:1460-1466. (SCI)
28. Kuo, C. F., J. J. Wu, K. Y. Lin, P. J. Tsai, S. C. Lee, Y. T. Jin, H. Y. Lei, and Y. S. Lin. 1998. Role of streptococcal pyrogenic exotoxin B in the mouse model of group A streptococcal infection. Infect. Immun. 66:3931-3935. (SCI)
29. Kuo, C. F., J. J. Wu, P. J. Tsai, F. J. Kao, H. Y. Lei, M. T. Lin, and Y. S. Lin. 1999. Streptococcal pyrogenic exotoxin B induces apoptosis and reduces phagocytic activity in U937 cells. Infect. Immun. 67:126-130. (SCI)
30. Lin, Y. S., Y. T. Huang, P. S. Chen, C. F. Lin, M. S. Jan, and H. Y. Lei. 1999. Requirement of I-E molecule for thymocyte apoptosis induced by staphylococcal enterotoxin B in vivo. Cell. Immunol. 193:71-79. (SCI)
31. Tsai, P. J., Y. S. Lin, C. F. Kuo, H. Y. Lei, and J. J. Wu. 1999. Group A streptococcus induces apoptosis in human epithelial cells. Infect. Immun. 67:4334-4339. (SCI)
32. Jan, M. S., H. S. Liu, and Y. S. Lin. 1999. Bad overexpression sensitizes NIH/3T3 cells to undergo apoptosis which involves caspase activation and ERK inactivation. Biochem. Biophys. Res. Commun. 264:724-729. (SCI)
33. Jan, M. S., L. Y. C. Wing, M. T. Lin, and Y. S. Lin. 1999. a-Difluoromethylornithine blocks thymocyte apoptosis via reduction of tyrosine phosphorylation. Scand. J. Immunol. 50:605-611. (SCI)
34. Lin, Y. S., H. L. Kuo, C. F. Kuo, S. T. Wang, B. C. Yang, and H. I. Chen. 1999. Antioxidant administration inhibits exercise-induced thymocyte apoptosis in rats. Med. Sci. Sports Exerc. 31:1594-1598. (SCI)
35. Lin, Y. L., C. C. Liu, H. Y. Lei, T. M. Yeh, Y. S. Lin, R. M. Y. Chen, and H. S. Liu. 2000. Infection of five human liver cell lines by dengue-2 virus. J. Med. Virol. 60:425-431. (SCI)
36. Hsu, L. J., M. S. Jan, and Y. S. Lin. 2000. In vivo staphylococcal enterotoxin B (SEB)-primed murine splenocytes secrete mediators which suppress CD25hi expression and cell cycle progression of naive splenocytes in response to SEB in vitro. Cell. Immunol. 201:50-57. (SCI)
37. Lin, Y. L., C. C. Liu, J. I. Chuang, H. Y. Lei, T. M. Yeh, Y. S. Lin, Y. H. Huang, and H. S. Liu. 2000. Involvement of oxidative stress, NF-IL-6 and RANTES expression in dengue-2 virus infected human liver cells. Virology 276:114-126. (SCI)
38. Huang, K. J., S. Y. J. Li, S. C. Chen, H. S. Liu, Y. S. Lin, T. M. Yeh, C. C. Liu, and H. Y. Lei. 2000. Manifestation of thrombocytopenia in dingue-2-virus-infected mice. J. General Virol. 81:2177-2182. (SCI)
39. Huang, Y. H., H. Y. Lei, H. S. Liu, Y. S. Lin, C. C. Liu, and T. M. Yeh. 2000. Dengue virus infects human endothelial cells and induces IL-6 and IL-8 production. Amer. J. Trop. Med. Hyg. 63:71-75. (SCI)
40. Lin, C. F., H. Y. Lei, C. C. Liu, H. S. Liu, T. M. Yeh, S. T. Wang, T. I. Yang, F. C. Sheu, C. F. Kuo, and Y. S. Lin. 2001. Generation of IgM anti-platelet autoantibody in dengue patients. J. Med. Virol. 63:143-149. (SCI)
41. Huang, Y. H., C. C. Liu, S. T. Wang, H. Y. Lei, H. S. Liu, Y. S. Lin, H. L. Wu, and T. M. Yeh. 2001. Activation of coagulation and fibrinolysis during dengue virus infection. J. Med. Virol. 63:247-251. (SCI)
42. Lei, H. Y., T. M. Yeh, H. S. Liu, Y. S. Lin, S. H. Chen, and C. C. Liu. 2001. Immunopathogenesis of dengue virus infection. J. Biomed. Sci. 8:377-388. (SCI)
43. Tsao, N., T. Y. Luh, C. K. Chou, J. J. Wu, Y. S. Lin, and H. Y. Lei. 2001. Inhibition of group A streptococcus infection by carboxyfullerene. Antimicrob. Agents Chemother. 45:1788-1793. (SCI)
44. Hsu, L. J., and Y. S. Lin. 2001. Roles of I-E molecule and CD28 costimulation in induction of suppression by staphylococcal enterotoxin B in vivo. Cell. Immunol. 212:35-43. (SCI)
45. Lin, C. F., H. Y. Lei, A. L. Shiau, H. S. Liu, T. M. Yeh, S. H. Chen, C. C. Liu, S. C. Chiu, and Y. S. Lin. 2002.Endothelial cell apoptosis induced by antibodies against dengue virus nonstructural protein 1 via production of nitric oxide. J. Immunol. 169:657-664. (SCI)
46. Sheu, B. S., J. J. Wu, C. Y. Lo, H. W. Wu, J. H. Chen, Y. S. Lin, and M. D. Lin. 2002. Impact of supplement with Lactobacillus- and Bifidobacterium-containing yogurt on triple therapy for Helicobacter pylori eradication. Aliment. Pharmacol. Ther. 16:1669-1675. (SCI)
47. Liu, C. C., K. J. Huang, Y. S. Lin, T. M. Yeh, H. S. Liu, and H. Y. Lei. 2002. Transient CD4/CD8 ratio inversion and immune deviation during dengue virus infection. J. Med. Virol. 68:241-252. (SCI)
48. Lin, Y. W., K. J. Wang, H. Y. Lei, Y. S. Lin, T. M. Yeh, H. S. Liu, C. C. Liu, and S. H. Chen. 2002. Virus replication and cytokine production in dengue virus-infected human B lymphocytes. J. Virol. 76:12242-12249. (SCI)
49. Lin, Y. L., H. Y. Lei, Y. S. Lin, T. M. Yeh, S. H. Chen, and H. S. Liu. 2002. Heparin inhibits dengue-2 virus infection of five human liver cell lines. Antiviral Res. 56:93-96. (SCI)
50. Lin, C. F., H. Y. Lei, A. L. Shiau, C. C. Liu, H. S. Liu, T. M. Yeh, S. H. Chen, and Y. S. Lin. 2003. Antibodies from dengue patient sera cross-react with endothelial cells and induce damage. J. Med. Virol. 69:82-90. (SCI)
51. Hor, W. S., W. L. Huang, Y. S. Lin, and B. C. Yang. 2003. Crosstalk between tumor cells and neutrophils through the Fas (APO-1, CD95)/FasL system: human glioma cells enhance cell viability and stimulate cytokine production in neutrophils. J. Leuko. Biol. 73:363-368. (SCI)
52. Luo, S. C., C. Y. Chen, Y. S. Lin, W. Y. Jeng, and W. J. Chuang. 2003. Backbone 1H, 15N and 13C resonance assignments of the 28 kDa mature form of streptopain. J. Biomol. NMR 25:165-166. (SCI)
53. Chen, C. Y., S. C. Luo, C. F. Kuo, Y. S. Lin, J. J. Wu, M. T. Lin, C. C. Liu, W. Y. Jeng, and W. J. Chung. 2003. Maturation processing and characterization of streptopain. J. Biol. Chem. 278:17336-17343. (SCI)
54. Tsao, C. W., J. T. Cheng, and Y. S. Lin. 2003. Down-regulation of Bcl-2, activation of caspases, and involvement of reactive oxygen species in 6-hydroxydopamine-induced thymocyte apoptosis. Neuroimmunomodulation 10:328-336. (SCI)
55. Huang, Y. H., H. Y. Lei, H. S. Liu, Y. S. Lin, S. H. Chen, C. C. Liu, and T. M. Yeh. 2003. Tissue plasminogen activator induced by dengue virus infection of human endothelial cells. J. Med. Virol. 70:610-616. (SCI)
56. Yan, J. J., C. C. Liu, W. C. Ko, S. Y. Hsu, H. M. Wu, Y. S. Lin, M. T. Lin, W. J. Chuang, and J. J. Wu. 2003. Molecular analysis of group A streptococcal isolates associated with scarlet fever in southern Taiwan between 1993 and 2002. J. Clin. Microbiol. 41:4858-4861. (SCI)
57. Hung, N. T., H. Y. Lei, N. T. Lan, Y. S. Lin, K. J. Huang, L. B. Lien, C. F. Lin, T. M. Yeh, D. Q. Ha, V. T. Q. Huong, L. C. Chen, J. H. Huang, L. T. My, C. C. Liu, and S. B. Halstead. 2004. Dengue hemorrhagic fever in infants: a study of clinical and cytokine profiles. J. Infect. Dis. 189:221-232. (SCI)
58. Lin, Y. S., C. F. Lin, H. Y. Lei, H. S. Liu, T. M. Yeh, S. H. Chen, and C. C. Liu. 2004. Antibody-mediated endothelial cell damage via nitric oxide. Curr. Pharm. Design 10:213-221. (review article) (SCI)
59. Kuo, C. F., Y. H. Luo, H. Y. Lin, K. J. Huang, J. J. Wu, H. Y. Lei, M. T. Lin, W. J. Chuang, C. C. Liu, Y. T. Jin, andY. S. Lin. 2004. Histopathologic changes in kidney and liver correlate with streptococcal pyrogenic exotoxin B production in the mouse model of group A streptococcal infection. Microb. Pathog. 36:273-285. (SCI)
60. Lin, C. F., C. L. Chen, W. T. Chang, M. S. Jan, L. J. Hsu, R. H. Wu, M. J. Tang, W. C. Chang, and Y. S. Lin. 2004. Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramide- and etoposide-induced apoptosis. J. Biol. Chem. 279:40755-40761. (SCI)
61. Tsai, W. H., C. W. Chang, W. J. Chuang, Y. S. Lin, J. J. Wu., C. C. Liu, W. T. Chang, and M. T. Lin. 2004. Streptococcal pyrogenic exotoxin B-induced apoptosis in A549 cells is mediated by a receptor- and mitochondrion-dependent pathway. Infect. Immun. 72:7055-7062. (SCI)
62. Lin, C. F., H. Y. Lei, H. S. Liu, T. M. Yeh, S. H. Chen, C. C. Liu, and Y. S. Lin. 2004. Autoimmunity in dengue virus infection. Dengue Bull. 28:51-57.
63. Lin, C. F., S. C. Chiu, Y. L. Hsiao, S. W. Wan, H. Y. Lei, A. L. Shiau, H. S. Liu, T. M. Yeh, S. H. Chen, C. C. Liu, and Y. S. Lin. 2005. Expression of cytokine, chemokine, and adhesion molecule during endothelial cell activation induced by antibodies against dengue virus nonstructural protein 1. J. Immunol. 174:395-403. (SCI)
64. Hsu, L. J., L. Schultz, J. Mattison, Y. S. Lin, and N. S. Chang. 2005. Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1. Biochem. Biophys. Res. Commun. 327:415-423. (SCI)
65. Hung, N. T., N. T. Lan, H.Y. Lei, Y. S. Lin, L. B. Lien, K. J. Huang, C. F. Lin, D. Q. Ha, V. T. Q. Huong, L. T. My, T. M. Yeh, J. H. Huang, C. C. Liu, and S. Halstead. 2005. Association between sex, nutritional status, severity of dengue hemorrhagic fever, and immune status in infants with dengue hemorrhagic fever. Am. J. Trop. Med. Hyg. 72:370-374. (SCI)
66. Lee, Y. R., K. J. Huang, H. Y. Lei, S. H. Chen, Y. S. Lin, T. M. Yeh, and H. S. Liu. 2005. Suckling mice were used to detect infectious dengue-2 viruses by intracerebral injection of the full-length RNA transcript. Intervirology 48:161-166. (SCI)
67. Wang, C. H., C. Y. Lin, Y. H. Luo, P. J. Tsai, Y. S. Lin, M. T. Lin, W. J. Chuang, C. C. Liu, and J. J. Wu. 2005.Effects of oligopeptide permease with group A streptococcal infections. Infect. Immun. 73:2881-2890. (SCI)
68. Kuo, C. F., C. C. Chen, Y. H. Luo, R. Y. Huang, W. J. Chuang, C. C. Sheu, and Y. S. Lin. 2005. Cordyceps sinensismycelium protects mice from group A streptococcal infection. J. Med. Microbiol. 54:795-802. (SCI)
69. Lin, C. F., C. L. Chen, W. T. Chang, M. S. Jan, L. J. Hsu, R. H. Wu, Y. T. Fang, M. J. Tang, W. C. Chang, and Y. S. Lin. 2005. Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation. J. Biol. Chem. 280:23758-23765. (SCI)
70. Lin, Y. S., C. F. Lin, Y. T. Fang, Y. M. Kuo, P. C. Liao, T. M. Yeh, K. Y. Hwa, C. C. K. Shieh, J. H. Yen, H. J. Wang, I. J. Su, and H. Y. Lei. 2005. Antibody to severe acute respiratory syndrome (SARS)-associated coronavirus spike protein domain 2 cross-reacts with lung epithelial cells and causes cytotoxicity. Clin. Exp. Immunol. 141:500-508. (SCI)
71. Huang, K. J., Y. C. Yang, Y. S. Lin, H. S. Liu, T. M. Yeh, S. H. Chen, C. C. Liu, and H. Y. Lei. 2005. Flow cytometric determination for dengue virus-infected cells: its application for antibody-dependent enhancement study. Dengue Bull. 29:1-10.
72. Chiang-Ni, C., C. H. Wang, P. J. Tsai, W. J. Chuang, Y. S. Lin, M. T. Lin, C. C. Liu, and J. J. Wu. 2006. Streptococcal pyrogenic exotoxin B causes mitochondria damage to polymorphonuclear cells preventing phagocytosis of group AStreptococcus. Med. Microbiol. Immun. 195:55-63. (SCI)
73. Tsao, N., W. H. Tsai, Y. S. Lin, W. J. Chuang, C. H. Wang, and C. F. Kuo. 2006. Streptococcal pyrogenic exotoxin B cleaves properdin and inhibits complement-mediated opsonophagocytosis. Biochem. Biophys. Res. Commun. 339:779-784. (SCI)
74. Tsao, C. W., Y. S. Lin, J. T Cheng, W. W. Chang, C. L. Chen, S. R. Wu, C. W. Fan, and H. Y. Lo. 2006. Serotonin transporter mRNA expression is decreased by lamivudine and ribavirin and increased by interferon in immune cells.Scand. J. Immunol. 63:106-115. (SCI)
75. Chen, L. C., H. Y. Lei, C. C. Liu, S. C. Shiesh, S. H. Chen, H. S. Liu, Y. S. Lin, S. T. Wang, H. W. Shyu, and T. M. Yeh. 2006. Correlation of serum levels of macrophage migration inhibitory factor with disease severity and clinical outcome in dengue patients. Am. J. Trop. Med. Hyg. 74:142-147. (SCI)
76. Huang, K. J., Y. C. Yang, Y. S. Lin, J. H. Huang, H. S. Liu, T. M. Yeh, S. H. Chen, C. C. Liu, and H. Y. Lei. 2006. The dual-specific binding of dengue virus and target cells for the antibody-dependent enhancement of dengue virus infection. J. Immunol. 176:2825-2832. (SCI)
77. Hung, N. T., N. T. Lan, H. Y. Lei, Y. S. Lin, L. B. Lien, K. J. Huang, C. F. Lin, D. Q. Ha, V. T. Q. Huong, L. T. My, T. M. Yeh, J. H. Huang, C. C. Liu, and S. B. Halstead. 2006. Volume replacement in infants with dengue hemorrhagic fever/dengue shock syndrome. Am. J. Trop. Med. Hyg. 74:684-691. (SCI)
78. Lin, C. F., S. W. Wan, H. J. Cheng, H. Y. Lei, and Y. S. Lin. 2006. Autoimmune pathogenesis in dengue virus infection. Viral Immunol. 19:127-132. (review article) (SCI)
79. Lin, C. F., C. L. Chen, and Y. S. Lin. 2006. Ceramide in apoptotic signaling and anticancer therapy. Curr. Med. Chem. 13: 1609-1616. (review article) (SCI)
80. Tsao, C. W., Y. S. Lin, C. C. Chen, C. H. Bai, and S. R. Wu. 2006. Cytokines and serotonin transporter in patients with major depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 30:899-905. (SCI)
81. Chen, C. L., C. F. Lin, C. W. Chiang, M. S. Jan, and Y. S. Lin. 2006. Lithium inhibits ceramide- and etoposide-induced PP2A methylation, Bcl-2 dephosphorylation, caspase-2 activation and apoptosis. Mol. Pharmacol. 70:510-517. (SCI)
82. Lee, Y. R., M. T. Liu, H. Y. Lei, C. C. Liu, J. M. Wu, Y. C. Tung, Y. S. Lin, T. M. Yeh, S. H. Chen, and H. S. Liu. 2006. MCP-1, a highly expressed chemokine in dengue haemorrhagic fever/dengue shock syndrome patients, may cause permeability change, possibly through reduced tight junctions of vascular endothelium cells. J. Gen. Virol. 87, 3623-3630. (SCI)
83. Kuo, C. F, C. C. Chen, C. F. Lin, M. S. Jan, R. Y. Huang, Y. H. Luo, W. J. Chuang, C. C. Sheu, and Y. S. Lin. 2007. Abrogation of streptococcal pyrogenic exotoxin B-mediated suppression of phagocytosis in U937 cells by Cordyceps sinensis mycelium via production of cytokines. Food Chem. Toxicol. 45:278-285. (SCI)
84. Chang, N. S., L. J. Hsu, Y. S. Lin, F. J. Lai, and H. M. Sheu. 2007. WW domain-containing oxidoreductase: a candidate tumor suppressor. Trends Mol. Med. 13:12-22. (review article) (SCI)
85. Chang, C. P., M. C. Yang, H. S. Liu, Y. S. Lin, H. Y. Lei. 2007. Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model. Hepatology 45:286-296. (SCI)
86. Chang, C. W., W. H. Tsai, W. J. Chuang, Y. S. Lin, J. J. Wu, C. C. Liu, P. J. Tsai, and M. T. Lin. 2007. The fate of SPE B after internalization and its implication in SPE B-induced apoptosis. J. Biomed. Sci. 14:419-427. (SCI)
87. Lee, Y. R., C. Y. Su, N. H. Chow, W. W. Lai, H. Y. Lei, C. L. Chang, T. Y. Chang, S. H. Chen, Y. S. Lin, T. M. Yeh, and H. S. Liu. 2007. Dengue viruses can infect human primary lung epithelia as well as lung carcinoma cells, and can also induce the secretion of IL-6 and RANTES. Virus Res. 126:216-225. (SCI)
88. Luo, Y. H., C. F. Kuo, K. J. Huang, J. J. Wu, H. Y. Lei, M. T. Lin, W. J. Chuang, C. C. Liu, C. F. Lin, and Y. S. Lin. 2007. Streptococcal pyrogenic exotoxin B antibodies in a mouse model of glomerulonephritis. Kidney Int. 72:716-724. (SCI)
89. Lin, C. F., C. L. Chen, C. W. Chiang, M. S. Jan, W. C. Huang, and Y. S. Lin. 2007. GSK-3b acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis. J. Cell Sci. 120:2935-2943. (SCI)
90. Lin, C. F., S. W. Wan, M. C. Chen, H. Y. Lei, and Y. S. Lin. 2007. Increased dengue virus-infected endothelial cell apoptosis caused by antibodies against nonstructural protein 1. Dengue Bull. 31:111-117.
91. Tsao, C. W., Y. S. Lin, J. T. Cheng, C. F. Lin, H. T. Wu, S. R. Wu, and W. H. Tsai. 2008. Interferon-a-induced serotonin uptake in Jurkat T cells via mitogen-activated protein kinase and transcriptional regulation of the serotonin transporter. J. Psychopharmacol. 22:753-760. (SCI)
92. Lei, H. Y., K. J. Huang, Y. S. Lin, T. M. Yeh, H. S. Liu, and C. C. Liu. 2008. Immunopathogenesis of dengue hemorrhagic fever. Am. J. Infect. Dis. 4:1-9. (review article)
93. Liu, C. C., K. J. Huang, M. C. Huang, J. J. Lin, S. M. Wang, J. W. Liu, J. J. Tsai, J. H. Huang, Y. S. Lin, H. S. Liu, T. M. Yeh, and H. Y. Lei. 2008. High case-fatality rate of adults with dengue hemorrhagic fever during an outbreak in non-endemic Taiwan: Risk factors for dengue-infected elders. Am. J. Infect. Dis. 4:10-17.
94. Lee, Y. R., N. T. Hung, C. C. Liu, K. J. Huang, H. Y. Lei, Y. S. Lin, J. R. Wang, T. M. Yeh, S. H. Chen, and H. S. Liu. 2008. Correlation of IFN-inducible protein 10 levels in sera with disease severity and clinical outcome of the dengue patients. Am. J. Infect. Dis. 4:18-21.
95. Chen, L. C., H. W. Shyu, H. Y. Lei, S. H. Chen, H. S. Liu, Y. S. Lin, and T. M. Yeh. 2008. Dengue virus infection induced NF-kB-dependent macrophage migration inhibitory factor production. Am. J. Infect. Dis. 4:22-31.
96. Lee, Y. R., H. Y. Lei, S. H. Chen, J. R. Wang, Y. S. Lin, T. M. Yeh, C. C. Liu, and H. S. Liu. 2008. Signaling pathways involved in dengue-2 virus infection induced RANTES over-expression. Am. J. Infect. Dis. 4:32-40.
97. Hung, N. T., N. T. Lan, Y. S. Lin, C. F. Lin, L. B. Lien, K. J. Huang, T. M. Yeh, D. Q. Ha, V. T. Q. Huong, L. C.Chen, L. T. My, J. H. Huang, C. C. Liu, and H. Y. Lei. 2008. Anti-platelet and anti-endothelial cell autoantibodies in Vietnamese infant and children with dengue hemorrhagic fever. Am. J. Infect. Dis. 4:41-49.
98. Huang, K. J., Y. S. Lin, H. S. Liu, T. M. Yeh, C. C. Liu, and H. Y. Lei. 2008. Generation of anti-platelet autoantibody during dengue virus infection. Am. J. Infect. Dis. 4:50-59.
99. Huang, K. J., Y. T. Chen, Y. S. Lin, J. H. Huang, H. S. Liu, T. M. Yeh, C. C. Liu, and H. Y. Lei. 2008. Anti-prM antibody as an autoantibody in dengue virus infection. Am. J. Infect. Dis. 4:60-68.
100. Lin, C. F., H. Y. Lei, C. C. Liu, H. S. Liu, T. M. Yeh, R. Anderson, and Y. S. Lin. 2008. Patient and mouse antibodies against dengue virus nonstructural protein 1 cross-react with platelets and cause their dysfunction or depletion. Am. J. Infect. Dis. 4:69-75.
101. Rai, C. I., H. Y. Lei, Y. S. Lin, H. S. Liu, S.H. Chen, L. C. Chen, and T. M. Yeh. 2008. Epitope mapping of dengue-virus-enhancing monoclonal-antibody using phage display peptide library. Am. J. Infect. Dis. 4:76-84.
102. Wan, S. W., C. F. Lin, M. C. Chen, H. Y. Lei, H. S. Liu, T. M. Yeh, C. C. Liu, and Y. S. Lin. 2008. C-terminal region of dengue virus nonstructural protein 1 is involved in endothelial cell cross-reactivity via molecular mimicry. Am. J. Infect. Dis. 4:85-91.
103. Kuo, C. F., Y. S. Lin, W. J. Chuang, J. J. Wu, and N. Tsao. 2008. Degrading complement 3 by streptococcal pyrogenic exotoxin B inhibits complement activation and neutrophil opsonophagocytosis. Infect. Immun. 76:1163-1169. (SCI)
104. Tsai, W. H., C. W. Chang, Y. S. Lin, W. J. Chuang, J. J. Wu, C. C. Liu, P. J. Tsai, and M. T. Lin. 2008. SPE B-induced apoptosis in A549 cells is mediated through avb3 integrin and Fas. Infect. Immun. 76:1349-1357. (SCI)
105. Wang, S. M., I. H. Lu, Y. L. Lin, Y. S. Lin, J. J. Wu, W. J. Chuang, M. T. Lin, and C. C. Liu. 2008. The severity ofStreptococcus pyogenes infections in children is significantly associated with plasma levels of inflammatory cytokines. Diagn. Microbiol. Infect. Dis. 61:165-169. (SCI)
106. Chen, C. L., C. F. Lin, W. T. Chang, W. C. Huang, C. F. Teng, and Y. S. Lin. 2008. Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway. Blood 111:4365-4374. (SCI)
107. Hsu, J. F., W. J. Chuang, S. C. Shiesh, Y. S. Lin, C. C. Liu, C. C. Wang, T. F. Fu, J. H. Tsai, W. L. Tsai, Y. J. Huang, Y. H. Hsieh, J. J. Wu, M. T. Lin, and W. Huang. 2008. Streptococcal pyrogenic exotoxin B cleaves human S-adenosylhomocysteine hydrolase and induces hypermethioninemia. J. Infect. Dis. 198:367-374. (SCI)
108. Hsu, L. J., Q. Hong, L. Schultz, E. Kuo, S. R. Lin, M. H. Lee, Y. S. Lin, and N. S. Chang. 2008. Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria. Cell. Signal. 20:1303-1312. (SCI)
109. Lee, Y. R., H. Y. Lei, M. T. Liu, J. R. Wang, S. H. Chen, Y. F. Jiang-Shieh, Y. S. Lin, T. M. Yeh, C. C. Liu, H. S. Liu. 2008. Autophagic machinery activated by dengue virus enhances virus replication. Virology 374:240-248. (SCI)
110. Tsou, C. C., C. Chiang-Ni, Y. S. Lin, W. J. Chuang, M. T. Lin, C. C. Liu, and J. J. Wu. 2008. An iron-binding protein, Dpr, decreases hydrogen peroxide stress and protects Streptococcus pyogenes against multiple stresses. Infect. Immun. 76:4038-4045. (SCI)
111. Lin, C. F., S. W. Wan, M. C. Chen, S. C. Lin, C. C. Cheng, S. C. Chiu, Y. L. Hsiao, H. Y. Lei, H. S. Liu, T. M. Yeh, and Y. S. Lin. 2008. Liver injury caused by antibodies against dengue virus nonstructural protein 1 in a murine model. Lab. Invest. 88:1079-1089. (SCI)
112. Chiang-Ni, C., C. C. Tsou, Y. S. Lin, W. J. Chuang, M. T. Lin, C. C. Liu, and J. J. Wu. 2008. The transcriptional terminator sequences downstream of the covR gene terminate covR/S operon transcription to generate covR monocistronic transcripts in Streptococcus pyogenes. Gene 427:99-103. (SCI)
113. Lin, H. C., S. M. Wang, Y. L. Lin, Y. S. Lin, J. J. Wu, W. J. Chuang, M. T. Lin, and C. C. Liu. 2008. Group A streptococcal infection caused by emm1 strains among children in southern Taiwan. Eur. J. Clin. Microbiol. Infect. Dis. 27:1253-1256. (SCI)
114. Cheng, H. J., C. F. Lin, H. Y. Lei, H. S. Liu, T. M. Yeh, Y. H. Luo, and Y. S. Lin. 2009. Proteomic analysis of endothelial cell autoantigens recognized by anti-dengue virus nonstructural protein 1 antibodies. Exp. Biol. Med. 234:63-73. (SCI)
115. Huang, W. C., Y. S. Lin, C. Y. Wang, C. C. Tsai, H. C. Tseng, C. L. Chen, P. J. Lu, P. S. Chen, L. Qian, J. S. Hong, and C. F. Lin. 2009. Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells. Immunology 127:601-612. (SCI)
116. Huang, W. C., Y. S. Lin, C. L. Chen, C. Y. Wang, W. H. Chiu, and C. F. Lin. 2009. Glycogen synthase kinase-3bmediates endoplasmic reticulum stress-induced lysosomal apoptosis in leukemia. J. Pharmacol. Exp. Ther. 329:524-531. (SCI)
117. Wang, C. C., H. C. Houng, C. L. Chen, P. J. Wang, C. F. Kuo, Y. S. Lin, J. J. Wu, M. T. Lin, C. C. Liu, W. Huang, and W. J. Chuang. 2009. Solution structure and backbone dynamics of streptopain: Insight into diverse substrate specificity. J. Biol. Chem. 284:10957-10967. (SCI)
118. Chen, L. C., H. W. Shyu, H. M. Lin, H. Y. Lei, Y. S. Lin, H. S. Liu, and T. M. Yeh. 2009. Dengue virus induces thrombomodulin expression in human endothelial cells and monocytes in vitro. J. Infect. 58:368-374. (SCI)
119. Hsu, L. J., L. Schultz, Q. Hong, K. Van Moer, J. Heath, M. Y. Li, F. J. Lai, S. R. Lin, M. H. Lee, C. P. Lo, Y. S. Lin, S. T. Chen, and N. S. Chang. 2009. Transforming growth factor b1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1. J. Biol. Chem. 284:16049-16059. (SCI)
120. Tsai, C. C., J. I. Kai, W. C. Huang, C. Y. Wang,Y. Wang, C. L. Chen, Y. T. Fang, Y. S. Lin, R. Anderson, S. H. Chen, C. W. Tsao, and C. F. Lin. 2009. Glycogen synthase kinase-3b facilitates IFN-g-induced STAT1 activation by regulating Src homology-2 domain-containing phosphatase 2. J. Immunol. 183:856-864. (SCI)
121. Su, Y. F., S. M. Wang, Y. L. Lin, W. J. Chuang, Y. S. Lin, J. J. Wu, M. T. Lin, and C. C. Liu. 2009. Changing epidemiology of Streptococcus pyogenes emm types and associated invasive and noninvasive infections in southern Taiwan. J. Clin. Microbiol. 47:2658-2661. (SCI)
122. Chen, M. C., C. F. Lin, H. Y. Lei, S. C. Lin, H. S. Liu, T. M. Yeh, R. Anderson, and Y. S. Lin. 2009. Deletion of the C-terminal region of dengue virus nonstructural protein 1 (NS1) abolishes anti-NS1-mediated platelet dysfunction and bleeding tendency. J. Immunol. 183:1797-1803. (SCI)
123. Chang, C. W., S. Y. Wu, W. J. Chuang, Y. S. Lin, J. J. Wu, C. C. Liu, P. J. Tsai, and M. T. Lin. 2009. The IL-8 production by streptococcal pyrogenic exotoxin B. Exp. Biol. Med. 234:1316-1326. (SCI)
124. Wang, C. Y., Y. S. Lin, W. C. Su, C. L. Chen, and C. F. Lin. 2009. Glycogen synthase kinase-3 and Omi/HtrA2 induce annexin A2 cleavage followed by cell cycle inhibition and apoptosis. Mol. Biol. Cell 20:4153-4161. (SCI)
125. Chiang-Ni, C., P. X. Zheng, Y. R. Ho, H. M. Wu, W. J. Chuang, Y. S. Lin, M. T. Lin, C. C. Liu, and J. J. Wu. 2009. emm1/sequence type 28 strains of group A streptococcus that express covR at early-stationary phase are associated with increased growth and earlier SpeB secretion. J. Clin. Microbiol. 47:3161-3169. (SCI)
126. Cheng, H. J., H. Y. Lei, C. F. Lin, Y. H. Luo, S. W. Wan, H. S. Liu, T. M. Yeh, and Y. S. Lin. 2009. Anti-dengue virus nonstructural protein 1 antibodies recognize protein disulfide isomerase on platelets and inhibit platelet aggregation.Mol. Immunol. 47:398-406. (SCI)
127. Chang, C. W., W. H. Tsai, W. J. Chuang, Y. S. Lin, J. J. Wu, C. C. Liu, P. J. Tsai, and M. T. Lin. 2009. Procaspase 8 and Bax are upregulated by distinct pathways in the SPE B-induced apoptosis. J. Biol. Chem. 284:33195-33205. (SCI)
128. Tsou, C. C., C. Chiang-Ni, Y. S. Lin, W. J. Chuang, M. T. Lin, C. C. Liu, and J. J. Wu. 2010. Oxidative stress and metal ions regulate a ferritin-like gene, dpr, in Streptococcus pyogenes. Int. J. Med. Microbiol. 300:259-264. (SCI)
129. Fang, Y. T., C. F. Lin, P. C. Liao, Y. M. Kuo, S. Wang, T. M. Yeh, C. C. K. Shieh, I. J. Su, H. Y. Lei, and Y. S. Lin. 2010. Annexin A2 on lung epithelial cell surface is recognized by severe acute respiratory syndrome-associated coronavirus spike domain 2 antibodies. Mol. Immunol. 47:1000-1009. (SCI)
130. Lin, W. C., C. F. Lin, C. L. Chen, C. W. Chen, and Y. S. Lin. 2010. Prediction of outcome in patients with acute respiratory distress syndrome by bronchoalveolar lavage inflammatory mediators. Exp. Biol. Med. 235:57-65. (SCI)
131. Luo, Y. H., W. J. Chuang, J. J. Wu, M. T. Lin, C. C. Liu, P. Y. Lin, J. N. Roan, T. W. Wong, Y. L. Chen, and Y. S. Lin. 2010. Molecular mimicry between streptococcal pyrogenic exotoxin B and endothelial cells. Lab. Invest. 90:1492-1505. (SCI)
132. Lin, C. C., Y. H. Huang, P. Y. Shu, H. S. Wu, Y. S. Lin, T. M. Yeh, H. S. Liu, C. C. Liu, and H. Y. Lei. 2010.Characteristic of dengue disease in Taiwan: 2002–2007. Am. J. Trop. Med. Hyg. 82:731-739. (SCI)
133. Chang, Y. P., C. C. Tsai, W. C. Huang, C. Y. Wang, C. L. Chen, Y. S. Lin, J. I. Kai, C. Y. Hsieh, Y. L. Cheng, P. C. Choi, S. H. Chen, S. P. Chang, H. S. Liu, and C. F. Lin. 2010. Autophagy facilitates IFN-g-induced JAK2-STAT1 activation and cellular inflammation. J. Biol. Chem. 285:28715-28722. (SCI)
134. Li, M. H., Y. H. Luo, C. F. Lin, Y. T. Chang, S. L. Lu, C. F. Kuo, J. S. Hong, and Y. S. Lin. 2011. Dextromethorphan efficiently increases bactericidal activity, attenuates inflammatory responses and prevents group A streptococcal sepsis. Antimicrob. Agent. Chemother. 55: 967-973. (SCI)
135. Lin, Y. S., T. M. Yeh, C. F. Lin, S. W. Wan, Y. C. Chuang, T. K. Hsu, H. S. Liu, C. C. Liu, R. Anderson, and H. Y. Lei. 2011. Molecular mimicry between virus and host and its implications for dengue disease pathogenesis. Exp. Biol. Med. 236: 515-523. (SCI) (review article)
136. Huang, W. C., C. L. Chen, Y. S. Lin and C. F. Lin. 2011. Apoptotic sphingolipid ceramide in cancer therapy. J. Lipids 2011:565316. Epub 2011 Jan 13. (review article)
137. Chuang, Y. C., H. Y. Lei, H. S. Liu, Y. S. Lin, T. F. Fu, and T. M. Yeh. 2011. Macrophage migration inhibitory factor induced by dengue virus infection increases vascular permeability. Cytokine 54:222-231. (SCI)
138. Huang, W. C., C. C. Tsai, C. L. Chen, T. Y. Chen, Y. P. Chen, Y. S. Lin, P. J. Lu, C. M. Lin, S. H. Wang, C. W. Tsao, C. Y. Wang, Y. L. Cheng, C. Y. Hsieh, P. C. Tseng, and C. F. Lin. 2011. Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis. FASEB J. 25:3661-3673. (SCI)
139. Chiang-Ni, C, A. B Wu, C. C. Liu, K. T. Chen, Y. S. Lin, W. J. Chuang, H. Y. Fang, and J. J. Wu. 2011. Emergence of uncommon emm types of Streptococcus pyogenes among adult patients in southern Taiwan. J. Microbiol. Immunol. Infect. 44(6):424-429. (SCI)
140. Lin, W. C., C. F. Lin, C. L. Chen, C. W. Chen, and Y. S. Lin. 2011. Inhibition of neutrophil apoptosis via sphingolipid signaling in acute lung injury. J. Pharmacol. Exp. Ther. 339:45-53. (SCI)
141. Chang, Y. P., C. L. Chen, S. O. Chen, Y. S. Lin, C. C. Tsai, W. C. Huang, C. Y. Wang, C. Y. Hsieh, P. C. Choi, and C. F. Lin. 2011. Autophagy facilitates an IFN-g response and signal transduction. Microbs Infect. 13:888-894. (review article) (SCI)
142. Tsai, C. C., W. C. Huang, C. L. Chen, C. Y, Hsieh, Y. S. Lin, S. H. Chen, K. C. Yang, and C. F. Lin. 2011. Glycogen synthase kinase-3 facilitates Con A-induced IFN-g-mediated immune hepatic injury. J. Immunol. 187:3867-3877. (SCI)
143. Cheng Y. L., W. C. Huang, C. L. Chen, C. C. Tsai, C. Y. Wang, W. H. Chiu, Y. L. Chen, Y. S. Lin, C. F. Chang, and C. F. Lin. 2011. Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli. Biochem. Biophys. Res. Commun. 412:334-340. (SCI)
144. Su, Y. F., W. J. Chuang, S. M. Wang, W. Y. Chen, C. Chiang-Ni, Y. S. Lin, J. J. Wu, and C. C. Liu. 2011. The deficient cleavage of M protein-bound IgG by IdeS: Insight into the escape of Streptococcus pyogenes from antibody-mediated immunity. Mol Immunol. 49:134-142. (SCI)
145. Chuang, Y. C., H. Y. Lei, Y. S. Lin, H. S. Liu, H. L. Wu, and T. M. Yeh. 2011. Dengue virus-induced autoantibodies bind to plasminogen and enhance its activation. J. Immunol. 187:6483-6490. (SCI)
146. Perng, G. C., H. Y. Lei, Y. S. Lin, K. Chokephaibulkit. 2011. Dengue vaccines: challenge and confrontation. World J. Vaccines 1:109-130.
147. Lin, S. W., Y. C. Chuang, Y. S. Lin, H. Y. Lei, H. S. Liu, and T. M. Yeh. 2012. Dengue virus nonstructural protein NS1 binds to prothrombin/thrombin and inhibits prothrombin activation. J. Infect. 64:325-334. (SCI)
148. Chiang-Ni, C., P. X. Zheng, P. J. Tsai, W. J. Chuang, Y. S. Lin, C. C. Liu, and J. J. Wu. 2012. Environmental pH changes, but not the LuxS signaling pathway, regulate SpeB expression in M1 group A streptococci. J. Med. Microbiol. 61:16-22. (SCI)
149. Fang, Y. T., C. F. Lin, C. Y., Wang, R. Anderson, and Y. S. Lin. 2012. Interferon-g stimulates p11-dependent surface expression of annexin A2 in lung epithelial cells to enhance phagocytosis. J. Cell. Physiol. 227:2775-2787. (SCI)
150. Wan, S. W., C. F. Lin, Y. T. Lu, H. Y. Lei, R. Anderson, and Y. S. Lin. 2012. Endothelial cell surface expression of protein disulfide isomerase activates b1 and b3 integrins and facilitates dengue virus infection. J. Cell. Biochem. 113:1681-1691. (SCI)
151. Chung, Y. C., W. H. Su, H. Y. Lei, Y. S. Lin, H. S. Liu, C. P. Chang, and T. M. Yeh. 2012. Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation. PLoS One 7(5):e37613. (SCI)
152. Hung, C. H., N. Tsao, Y. F. Zeng, S. L. Lu, C. Chiang-Ni, Y. S. Lin, J. J. Wu, and C. F. Kuo. 2012. Synergistic effects of streptolysin S and streptococcal pyrogenic exotoxin B on the mouse model of group A streptococcal infection. Med. Microbiol. Immunol. 201:357-369. (SCI)
153. Hsieh, C.Y., C. L. Chen, C. C. Tsai, W. C. Huang, P. C. Tseng, Y. S. Lin, S. H. Chen, T. W. Wong, P. C. Choi, and C. F. Lin. 2012. Inhibiting glycogen synthase kinase-3 decreases 12-O-tetradecanoylphorbol-13-acetate-induced interferon-γ-mediated skin inflammation. J. Pharmacol. Exp. Ther. (in press) (SCI)
154. Yang, T.T., C. L. Chen, W. C. Lin, Y. S. Lin, P. C. Tseng, C. Y. Hsieh, Y. H. Chen, W. C. Huang, C. C. Tsai, C. Y.,Wang, C. C. Shieh, and C. F. Lin. 2012. Glycogen synthase kinase-3b inactivation is an intracellular marker and regulator for endotoxemic neutrophilia. J. Mol. Med. (in press) (SCI)
155. Wang, C. Y., C. L. Chen, Y. L. Tseng, Y. T. Fang, Y. S. Lin, W. C. Su, C. C. Chen, K. C. Chang, Y. C. Wang, and C. F. Lin. 2012. Annexin A2 silencing induces G2 arrest of non-small cell lung cancer cells through p53-dependent and -independent mechanisms. J. Biol. Chem. (in press) (SCI)
Book chapters
1. Lin, C. F., R. Anderson, and Y. S Lin. Dengue virus-induced autoimmunity and its pathogenic effects. Dengue Disease. Research Signpost, 2008.
2. Anderson, R., C. F. Lin, and Y. S. Lin. Vascular endothelial dynamics in dengue pathogenesis. Dengue Disease. Research Signpost, 2008.