小檔案

學 歷

美國伊利諾大學芝加哥分校微免所博士

成功大學物理系學士 

經 歷

成功大學微免所教授

成功大學微免所副教授 

成功大學微免所助理教授 

美國史丹佛大學博士後研究員

美國加州柏克萊國家實驗室博士後研究員

研究興趣

結合X-ray蛋白質結晶學 (Protein Crystallography)和溶液小角度散射 (Small-Angle X-ray Scattering)的技術，探討蛋白質的三度空間結構和功能，以及蛋白質和蛋白質、蛋白質和核酸之間的交互作用。

研究主題

1. 探討A型鏈球菌毒力因子的結構基礎以及調控網絡，理解這些分子對於A型鏈球菌的細胞內發病機制的作用模式。
2. 探討介白素1家族(Interleukin 1 family) 細胞激素受體之結構彈性與辨認受質功能之關係。
3. 探討登革病毒疫苗研發之結構基礎。

PUBLICATIONS

1. Research NCKU! https://researchoutput.ncku.edu.tw/zh/persons/shu-ying-wang

邀請報告

1.        Solution Structures of the IL-33 Signaling Complex and Receptors.  2013.  The 20^th Users’ Meeting, National Synchrotron Radiation Research Center, Hsinchu, Taiwan.

2.        Small-angle X-ray Scattering studies on the IL-1 signaling complex.  2012.  The 17^th Biophysics Conference, Academia Sinica, Taipei, Taiwan.

3.        Solution architecture of Interleukin 1 signaling complex by SAXS analysis.  2011.  The 17^thUsers’ Meeting, National Synchrotron Radiation Research Center, Hsinchu, Taiwan.

4.        Solution structural studies of a flexible RNA helicase YxiN by small-angle X-ray Scattering. 2011. School of Life Sciences, Tsinghua University, Beijing, China.

5.        Solution structure of the Bacillus subtilis RNA helicase YxiN.  2010.  The 5th AOFSRR & The 22nd PAL User’s Joint Conference, Pohang, Korea.

6.        Solution structure of the Bacillus subtilis RNA helicase YxiN.  2010.  The Fourth Taiwan-Japan Workshop on Neutron and X-ray Scattering, Yilan, Taiwan.

7.        SAXS studies on the conformational changes of a FRET-based sensor protein.  2009. The 15^thUsers’ Meeting, National Synchrotron Radiation Research Center, Hsinchu, Taiwan.

會議演講

1.        Solution Structure of the IL-33 Signaling Complex.  2013.  Lecture presentation.  The Annual Meeting of the American Crystallographic Association, Honolulu, Hawaii, USA.

2.        Wang, S., Baral, T. N., Chao, S. -Y., Li, S., Tanha, J., Arbabi-Ghahroudi, M. and Zhang, J. 2011.  Crystal Structure of a Dimeric Anti-HER2 Human Single Domain Antibody.     Poster presentation.  The XXII International Congress and General Assembly of the International Union of Crystallography, Madrid, Spain.

3.        Wang, S., Chao, S. -Y., Tsao, C. -C. and Wu, J. -J.  2010.  Crystal Structure of the Stress Response Regulator PerR from Streptococcus pyogenes.  Poster presentation.  The Annual Meeting of the American Crystallographic Association, Chicago, IL, USA.

4.        Wang, S., Overgaard, M., Hu, Y. and McKay, M.  2009.  Solution Small-Angle X-ray Scattering Studies of a Multidomain RNA Helicase, the Bacilius subtilis YxiN Protein.   Poster presentation.  XIV International Conference on Small-Angle Scattering, Oxford, UK.

專業培訓

1.        Workshop on Small-Angle X-ray Scattering and Diffraction Studies in Structural Biology, Stanford Synchrotron Radiation Laboratory, CA, USA, July 2006.

2.        ACA Summer Course in X-ray Crystallography, X-ray Crystallography Center, University of Georgia, Athens, GA, USA, July 2000.